KlamAV

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Magazine Linux Format raves KlamAV is a "wonderful... a polished front-end for KDE that makes ClamAV feel more like the commercial applications you find on other operating systems"

KlamAV is an anti-virus manager that allows you to manage your virus-scanning, scheduling, and software/database updates.

KlamAV features manual scanning, context-menu scanning, quarantine management, virus browser, mail scanning (KMail and Evolution) and scan scheduler.

Similar applications: 
Norton AntiVirus, McAfee Antivirus, AVG